The Brazil international was a key part of the Italian side's Champions League win two years ago but now looks set to leave the San Siro.
Samir Handanovic arrived from Udinese this summer and Cesar has been allowed to speak to other clubs about a move.
Tottenham have been heavily linked with the 32-year-old but it is understood that QPR are in talks with the Inter goalkeeper.
The west Londoners' technical director Mike Rigg is speaking with Cesar's representatives to see whether a move to Loftus Road can be pushed through.
The news comes just days after summer signing Rob Green's blunder set Swansea on course for a surprise 5-0 victory at QPR.
The defeat also saw manager Mark Hughes step up his search for defensive reinforcements, and talks with Tottenham club captain Michael Dawson and Real Madrid's Ricardo Carvalho are understood to be ongoing.